Synbiotic more effective for weight management over probiotic alone, study suggests

Furthermore, the researchers note marked reductions in triglyceride levels by week eight of the intervention, as well as significant increases of bifidobacterial in the faecal samples.

The Japanese researchers conclude: “The results suggest that the combined intake of GCL2505 and inulin suppresses the accumulation of visceral fat more compared with the intake of GCL2505 alone.

“In terms of preventing the development of metabolic abnormalities, reducing visceral fat is relatively more important than weight or body fat. It is thought that the combined intake of GCL2505 and inulin, which are functional food components that can be easily applied to daily life, may help to prevent the development of metabolic abnormalities in overweight adults,” they add, emphasising the signficance of the findings.

Obesity prevalence

With the prevalence of obesity almost tripling between the years of 1975 and 2016, those now at increased risk of developing associated lifestyle diseases such as hypertension, dyslipidaemia, and diabetes, as well as noncommunicable diseases, has vastly increased.

Thus, there is an increased need for natural and effective lifestyle solutions to the modern-day obesity epidemic. Evidence​ has established a significant link between the gut microbiota and obesity, and thus, there has been a strong interest in biotics for the treatment of overweight and obesity.

Previous studies​ investigating probiotics containing lactic acid bacteria and Bifidobacterium have noted significant reductions in body weight, body fat percentage, and waist circumference. In addition, multiple meta-analyses​ have shown the effectiveness of prebiotics in reducing body weight, BMI, fasting glucose, and fasting triglyceride levels.